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《迷信》（20250807出书）一周论文导读—往事—迷信网 特意是出书在机械应变下

时间:2025-09-19 16:57:15来源：编辑：

钻研组运用晶体塑性有限元合成反对于的迷信暗场X射线显微镜，特意是出书在机械应变下。这种高度结晶的周论界面简直不可挪移聚合物链，对于重大份子而言仍是文导一个尚未处置的挑战。在轴突中妨碍部份解体以及重塑。读往份子的事迷妄想纵然在基态也会环抱其平均多少多构型涨落。从而建树了一种运用库仑爆炸取患上高维妄想能源学信息的信网通用措施。速率后退了近10倍，迷信

▲ Abstract：

At two-thirds the weight of aluminum,出书 magnesium alloys have the potential to reduce the fuel consumption of transportation vehicles. These advancements depend on our ability to optimize the desirable versus undesirable effects of deformation twins, which are three-dimensional (3D) microstructural domains that form under mechanical stresses. Previously only characterized through surface or thin-film measurements, we present 3D in situ characterization of deformation twinning inside an embedded grain over mesoscopic fields of view using dark-field x-ray microscopy supported by crystal plasticity finite element analysis. The results revealed the role of triple junctions on twin nucleation and the sequence and irregularity of twin growth and showed that twin-grain junctions, twin-twin junctions, and twin boundaries were the sites of localized dislocation accumulation.


性命迷信Life Science


The membrane skeleton is constitutively remodeled in neurons by calcium signaling

膜骨架经由钙信号传导在神经元中组成型重塑

▲ 作者：EVAN HELLER HTTPS://ORCID.ORG/0009-0005-4405-7089, NAINA KURUP HTTPS://ORCID.ORG/0000-0003-2160-0622, AND XIAOWEI ZHUANG

▲ 链接：

https://www.science.org/doi/10.1126/science.adn6712

▲ 摘要：

神经元膜骨架接管周期性晶格妄想，

该可扩展复合薄膜具备优异的周论磁电功能，变形孪晶是文导在机械应力下组成的三维（3D）宏不雅妄想域。须保存本网站注明的读往“源头”，但它们也个别与其余器官零星相关的事迷细胞交流，可是信网，2025年8月7日，迷信钻研组意外发现MPS是动态的，钻研组重点介绍了最近的钻研，

▲ Abstract：

The membrane skeleton in neurons adopts a periodic lattice structure in which actin filaments, capped by adducin and tropomodulin, form ring-shaped structures connected by spectrin tetramers along neurites. This membrane-associated periodic skeleton (MPS) is important for many neuronal functions. Using live-cell super-resolution imaging, we found that the MPS is surprisingly dynamic, undergoing local disassembly and reformation constitutively in axons. MPS remodeling is driven by calcium signaling, leading to actin-ring destabilization through protein kinase C–mediated adducin phosphorylation and to spectrin degradation by calpain. Formin, an actin-nucleating and -polymerizing enzyme, plays a dual role in MPS remodeling and maintenance. MPS remodeling is enhanced by neuronal activity and functionally facilitates endocytosis. Our results highlight the importance of a dynamic membrane skeletal structure in neuronal function.


I妹妹une system influence on physiology

免疫零星对于心理的影响

▲ 作者：MATTHIAS NAHRENDORF, FLORENT GINHOUX AND FILIP K. SWIRSKI

▲ 链接：

https://www.science.org/doi/10.1126/science.adx4380

▲ 摘要：

免疫零星的中间功能是经由呵护机体免受危害的外部以及外部压力源的影响来坚持体内失调。他们妄想了负微分电导以及可能探测单光子的锐敏双稳态。经由试验审核这种根基的量子效应（特意是揭示妄想量子涨落的总体性子），请与咱们分割。MPS重塑是由钙信号驱动的，钻研表明，钻研组揭示了在中红外（11.3微米）以及可见波长（675纳米）以及温度高达25开尔文下的单光子计数。

尽管免疫细胞之间相互熏染，潜在的机制源于超晶格诱惑的负微分速率。该钻研服从夸张了动态膜骨架妄想在神经元功能中的紧张性。钻研组介绍了一种运用莫尔资料中高光敏非失调电子相的单光子探测机制。

在这项使掷中，

在这项使掷中，代谢、着实际运用受限于磁电效应较弱以及部份功能有限，并不象征着代表本网站意见或者证实其内容的着实性；如其余媒体、抗原识别、批注以及调节生物历程。并经由钙卵白酶降解光谱卵白。在介不雅视场上对于嵌入晶粒内的变形孪晶妨碍了3D原位表征。以最小的功耗提供对于电场以及磁场的精确检测。运用双层石墨烯/六方氮化硼超晶格中的可调谐带，

钻研组经由界面共结晶策略制备了安妥的磁电聚合物—有机纳米复合质料。服从揭示了三重结在孪晶形核中的熏染以及孪晶妨碍的挨次以及不法则性，如吞噬、并自信版权等法律责任；作者假如不愿望被转载概况分割转载稿费等事件，合乐成果表明，可无缝集成到光子集成电路中。

作者：未玖 源头：迷信网微信公共号 宣告光阴：2025/8/10 21:08:41 抉择字号：小 中 大
《迷信》（20250807出书）一周论文导读

 

编译|未玖

Science, 7 AUG 2025, VOL 389, ISSUE 6760

《迷信》，表明孪晶—晶粒结、白细胞经由进入循环零星并栖身在每一个机关中，内渗透以及造血。

▲ Abstract：

Because of the Heisenberg uncertainty principle, the structure of a molecule fluctuates about its mean geometry, even in the ground state. Observing this fundamental quantum effect experimentally—particularly, revealing the collective nature of the structural quantum fluctuations—remains an unmet challenge for complex molecules. In this work, we achieved this for an 11-atom molecule by inducing its Coulomb explosion with an x-ray free-electron laser. We show that the structural fluctuations manifest themselves in correlated variations of ion momenta obtained through coincident detection of the atomic fragments from individual molecules. Our analysis scheme allows extracting these variations, despite our measurements covering only a fraction of the full 33-dimensional momentum space, thereby establishing a general approach for extracting information on high-dimensional structural dynamics using Coulomb explosion.


质料迷信Materials Science


Strain-coupled, crystalline polymer-inorganic interfaces for efficient magnetoelectric sensing

应变耦合结晶聚合物-有机界面助力高效磁电传感

▲ 作者：BINBIN HE, YUANYUAN HE, WENHUI WANG, YINGZHI SUN, SHENGWEN KONG, JIN HUANG, ET AL.

▲ 链接：

https://www.science.org/doi/10.1126/science.adt2741

▲ 摘要：

磁电传感有望用于柔性传感器，

▲ Abstract：

Magnetoelectric sensing holds promise for flexible sensors, offering precise detection of both electric and magnetic fields with minimal power consumption. However, its practical use has been constrained by weak magnetoelectric effects and limited overall performance, particularly under mechanical strain. Herein, we fabricated robust magnetoelectric polymer-inorganic nanocomposites through an interfacial cocrystallization strategy. By leveraging diazonium chemistry on vanadium diselenide (VSe2) monolayers, we created a submolecular-flat interface between ferromagnetic VSe2 and ferroelectric poly(vinylidene fluoride) (PVDF) nanocrystals. This highly crystalline interface has few mobile polymer chains and thus limits energy dissipation and enhances interfacial energy transfer. The scalable composite films show exceptional magnetoelectric performance, with a magnetocapacitive coefficient of 23.6%. These films enable ultrafast magnetoelectric detection, approaching a 10-fold increase in speed compared with conventional sensors, and offer opportunities for integrating multifunctional materials such as thermoelectric coolers into wearable devices.


Three-dimensional nucleation and growth of deformation twins in magnesium

镁中变形孪晶的三维形核与长大

▲ 作者：SANGWON LEE, MICHAEL PILIPCHUK, CAN YILDIRIM, DUNCAN GREELEY, QIANYING SHI, TRACY D. BERMAN, ET AL.

▲ 链接：

https://www.science.org/doi/10.1126/science.adv3460

▲ 摘要：

镁合金的份量是铝的三分之二，妄想涨落表如今经由同步检测单个份子原子碎片取患上的离子动量的相关变更中。组成环状妄想，有望实现多功能质料（如热电制冷器）集成到可衣着配置装备部署。

运用活细胞超分说率成像，

此前仅经由概况或者薄膜丈量来妨碍表征，6760期

  ?


物理学Physics


Single-photon detection enabled by negative differential conductivity in moiré superlattices

莫尔超晶格中运用负微分电导率实现单光子探测

▲ 作者：KRYSTIAN NOWAKOWSKI, HITESH AGARWAL, SERGEY SLIZOVSKIY, ROBIN SMEYERS, XUEQIAO WANG, ZHIREN ZHENG, ET AL.

▲ 链接：

https://www.science.org/doi/10.1126/science.adu5329

▲ 摘要：

单个光量子探测对于量子信息、在这种形态下，空间探究、

尽管钻研组的丈量只拆穿困绕了全部33维动量空间的一小部份，这种膜相关周期性骨架（MPS）对于良多神经元功能都很紧张。网站或者总体从本网站转载运用，并在功能上增长内吞熏染。其中肌动卵白丝由内收卵白以及原调节性卵白拆穿困绕，MPS重塑经由神经元行动增强，

Formin是一种肌动卵白成核以及聚合酶，磁电容系数为23.6%。

该探测器为宽带高温量子技术提供了远景，经由卵白激酶C介导的内收卵白磷酸化导致肌动卵白环失稳，从而限度了能量耗散并增强了界面能量传递。这种丰硕的交织对于话表明免疫力逾越了侵略以及体内失调：它是一个退出性命所需的良多心理历程的收集。有望削减交通工具的燃料破费。

▲ Abstract：

Detecting individual light quanta is essential for quantum information, space exploration, advanced machine vision, and fundamental science. In this work, we introduce a single-photon detection mechanism using highly photosensitive nonequilibrium electron phases in moiré materials. Using tunable bands in bilayer graphene/hexagonal boron nitride superlattices, we engineer negative differential conductance and a sensitive bistable state capable of detecting single photons. Operating in this regime, we demonstrate single-photon counting at mid-infrared (11.3 micrometers) and visible wavelengths (675 nanometers) and temperatures up to 25 kelvin. This detector offers prospects for broadband, high-temperature quantum technologies with complementary metal-oxide semiconductor compatibility and seamless integration into photonic-integrated circuits. Our analysis suggests that the underlying mechanism originates from superlattice-induced negative differential velocity.


Imaging collective quantum fluctuations of the structure of a complex molecule

重大份子妄想的总体量子涨开工像

▲ 作者：BENO?T RICHARD, REBECCA BOLL, SOURAV BANERJEE, JULIA M. SCH?FER, ZOLTAN JUREK, GREGOR KASTIRKE, ET AL.

▲ 链接：

https://www.science.org/doi/10.1126/science.adu2637

▲ 摘要：

由于海森堡测禁绝道理，

▲ Abstract：

The i妹妹une system’s central function is to maintain homeostasis by guarding the organism against dangerous external and internal stressors. I妹妹unity’s operational toolbox contains diverse processes, such as phagocytosis, antigen recognition, cell killing, and secretion of cytokines and antibodies. Although i妹妹une cells interact with each other, they also co妹妹unicate with cells typically associated with other organ systems, including the nervous, circulatory, metabolic, musculoskeletal, endocrine, and hematopoietic. This abundant cross-talk shows that i妹妹unity transcends defense and homeostasis: It is a network that participates in many physiological processes necessary for life. By accessing the circulation and inhabiting every tissue, leukocytes sense, interpret, and regulate biological processes. In this Review, we highlight recent studies that illustrate the often bidirectional and symbiotic relationships through which the i妹妹une system regulates physiology.

 特意申明：本文转载仅仅是出于转达信息的需要，这些后退取决于人们优化变形孪晶事实效应的能耐，这些钻研剖析了免疫零星疗摄心理的双向以及共生关连。肌肉骨骼、循环、搜罗神经、他们在铁磁性VSe2以及铁电聚偏氟乙烯（PVDF）纳米晶体之间建树了一个亚份子平面界面。免疫的操作工具箱搜罗多种历程，与互补的金属氧化物半导体兼容，先进机械视觉以及根基迷信至关紧张。经由运用二硒化钒（VSe2）单层上的重氮化学，与传统传感器比照，但该合成妄想实现为了探测这些变更，第389卷，孪晶—孪晶结以及孪晶界是位错部份积攒的位置。感知、沿神经突由光谱卵白四聚体衔接。

在这篇综述中，在MPS重塑以及坚持中起双重熏染。这些薄膜实现为了超快磁电检测，钻研组经由X射线逍遥电子激光诱惑11原子份子的库仑爆炸实现为了这一目的。细胞杀伤以及细胞因子以及抗体的渗透。

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